Abstract：Objective To assess the value of diffusion-weighted imaging (DWI) infarct volume and infarct volume growth in
predicting the functional outcome of acute stroke patients receiving endovascular therapy. Methods A total of 38 stroke patients
receiving endovascular therapy in our hospital were prospectively enrolled. The onset time of all patients was within 6 hours. All
patients received MRI examination before and after treatment within 24 h. The DWI volume on admission (VD1), DWI volume on
follow-up (VD2), DWI volume growth (VDWI-G), the functional outcome at 3 months (mRS) and other clinical data were collected.
The difference of parameters between the good prognosis group and the bad prognosis group, the value of DWI infarct volume and
infarct volume growth in predicting the prognosis of stroke were statistically analyzed. Results Of the 38 patients, 23 (60.53%) had
good outcome and 15 (39.47%) had poor outcome. Compared with the bad prognosis group, the good prognosis group had a smaller
VD1 [(13.54±15.17) mL vs. (59.32±53.27) mL; P<0.001], VD2 [(28.04±21.72) mL vs. (107.69±90.37) mL; P<0.001] and VDWI-G
[(14.50±17.88) mL vs. (48.37±42.89) mL; P=0.010]. Spearman’s rank correlation analysis revealed that VD1 (r=0.414, P=0.010),
VD2 (r=0.486, P=0.002) and VDWI-G (r=0.467, P=0.003) were all positively correlated with mRS at 3 months. Receiver operating
characteristic curve analysis showed that when the optimal cut-off value of VD1 was 33.50 mL, the sensitivity and specificity for
predicting functional outcome was 60.00% and 95.65% respectively; when the optimal cut-off value of VD2 was 32.80 mL, the
sensitivity and specificity was 80.00% and 78.26%; when the optimal cut-off value of VDWI-G was 13.2 mL, the sensitivity and
specificity was 86.70% and 60.87% respectively. Conclusion Evaluating DWI volume on admission, DWI volume on follow-up, DWI
volume growth comprehensively may be useful in predicting the functional outcome of acute stroke patients after endovascular therapy.
邱建博，陈广浩，黄红涛，高伟. DWI梗死体积与体积增长在评估卒中血管再通术后预后中的价值[J]. 中国医疗设备, 2020, 35(4): 55-59.
QIU Jianbo, CHEN Guanghao, HUANG Hongtao, GAO Wei. The Predict Value of DWI Infarct Volume and Volume Growth in the Functional Outcome of
Stroke After Endovascular Therapy. China Medical Devices, 2020, 35(4): 55-59.
