Abstract：Objective To analyze the stability and practicability of positron medicine synthesizer (F300E-2) during installation and use
processes. Methods Based on F300E-2 synthesizer and its synthesis technology, the synthetic yield and quality testing of 18F-FDG
were carried out, and quality control of 18F-FDG was performed. Results Synthetic yield of 18F-FDG samples distributed mainly
in 42.80%~64.60%, among which 91.01% samples’ synthetic yield over 55%, and 50.56% samples’ synthetic yield over 60%. The
quality control results showed that all batches of 18F-FDG samples were colorless transparent solution, with pH=6.7~7.0 and radiochemical
purity more than 98%. The radionuclide half-life were 109.652 min and 112.135 min by linear fitting method and exponential fitting
method. Conclusion F300E-2 synthesizer has the advantages of high yield, stable performance and strong practicability, and all the
quality control indexes of its synthetic products are in line with standards of pharmacopoeia.
廖光星，何正中，李宁，杨鸿宇，肖国有，罗煜，姚忠强，李党生. 住友F300E-2自动合成18F-FDG及质量控制[J]. 中国医疗设备, 2019, 34(9): 45-48.
LIAO Guangxing, HE Zhengzhong, LI Ning, YANG Hongyu, XIAO Guoyou, LUO Yu, YAO Zhongqiang, LI Dangsheng. Automatic Synthesis and Quality Control of 18F-FDG Using SUMITOMO F300E-2. China Medical Devices, 2019, 34(9): 45-48.
