Registration Algorithm of DBS Preoperative Image and ICBM-152 Atlas
NI Yangyang1, ZHENG Huifen2, CAO Shengwu3, LUO Shouhua1
1.School of Biological Sciences and Medical Engineering, Southeast University, Nanjing Jiangsu 210096, China; 2.Department of
Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing Jiangsu 210029, China; 3.Department
of Neurosurgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing Jiangsu 210029, China
Abstract：Deep brain stimulation (DBS) surgical treatment is an important treatment for patients with Parkinson’s disease. One of
the effective ways of preoperative navigation and nuclei identification for DBS is to perform registration between brain atlases and
preoperative images. In this paper, we initially implemented the registration of preoperative images and ICBM-152 atlas. We firstly
normalized the preoperative clinical image to the coordinate space of the atlas, and then used piecewise linear registration to coarsely
map the spectrum, at last, non-rigid registration of the brain atlas with preoperative data was achieved using mutual information as
a measure of similarity. Thereby a personalized brain atlas could be calculated for each patient, the experimental results showed that
the mutual information between the image and the atlas was 0.558 in the initial stage of the experiment, while it increased to 1.217
when the proposed method was employed.
倪杨阳1，郑慧芬2，曹胜武3，罗守华1. DBS术前图像与ICBM-152图谱的配准算法[J]. 中国医疗设备, 2018, 33(7): 44-47.
NI Yangyang1, ZHENG Huifen2, CAO Shengwu3, LUO Shouhua1. Registration Algorithm of DBS Preoperative Image and ICBM-152 Atlas. China Medical Devices, 2018, 33(7): 44-47.