Abstract:Objective This study aimed to assess the feasibility of auto-planning (AP) technology in lung cancer by comparing the
dosimetry differences between the AP plan and the manual plan. Methods Sixteen lung cancer patient were selected to perform the
AP plan and manual plan designing by Pinnacle3 V9.10 treatment planning. Of the sixteen patients, eight had right tumors, eight
had left tumors and two had central tumors. Two plans were compared among target dose distribution and the doses received by the
organs at risk (OARs). Results Compared with the manual plan, the AP plan improved the minimum dose of targets, the mean dose
was closer to the prescription dose, and it could also provide a better conformity. The maximum doses and mean dose for spinal
cord were considerably lower than the manual plan. The mean dose, V30, and V20 of the total lungs were slightly lower in AP groups.
Supper results were also found in mean dose and V40 for heart. The differences were all statistically significant. Conclusion AP plan
can achieve the requirement of clinical dose distribution as the manual plan. In addition, the AP groups can improve the minimum
dose and conformity in the target region. The radiation dose on the spinal cord and total lung are reduced at the same time.
李慧君,王琳婧,王锐濠,张书旭. Auto-Planning在肺癌调强放疗计划中的剂量学研究[J]. 中国医疗设备, 2018, 33(6): 82-84.
LI Huijun, WANG Linjing, WANG Ruihao, ZHANG Shuxu. Dosimetric Study of Auto-Planning for Intensity-Modulated Radiation Therapy of Lung Cancer. China Medical Devices, 2018, 33(6): 82-84.