Abstract：Objective According to the kidney scintigraphy, the depth of the kidney was measured by the
method of nuclear medicine. The effects of kidney depth and the difference of double kidney depth on
glomerular filtration rate (GFR) measured by Gates renal dynamic imaging were explored. Investigate the
significance of renal dynamic imaging. Methods 118 patients who underwent radionuclide kidney dynamic
imaging from February to December 2015 were selected, and the depth of the kidney and the difference
of the depth of the double kidneys (D) were measured by renal side imaging, the corrected GFR and renal
GFR were obtained. The Gates method defaults the Tonnesen formula to estimate the depth of the kidney
and obtains uncorrected depth GFR and renal GFR. The correlation between uncorrected and corrected
GFR and creatinine clearance rate (Ccr) were anlysed, and the effect of the double renal depth difference
on the renal function was measured. Results Compared with renal lateral imaging, the renal depth and
the depth difference were underestimated by Tonnesen formulation. The uncorrected GFR by Tonnesen
formulation and GFR corrected by renal lateral imaging were positively correlated with Ccr (r=0.760 and
0.755, respectively). The uncorrected GFR was lower than corrected GFR, but without statistical significance
difference. The variant of split function estimated by renal lateral imaging compared to Tonnesen formulation
was positively correlated with the depth difference (r=0.98, P<0.01), with the increase of the depth
difference, Tonnesen formulation was difficult to accurately reflect the variant of split function. In the group
with a smaller difference (D<0.5 cm), the uncorrected and corrected GFR had no statistically significant
difference. While in the group with a larger difference (D≥0.5 cm), the two were significantly different.
Conclusion Direct measurement of renal depth from renal lateral imaging can improve the accuracy of split
renal GFR, especially in patients with a remarkable difference between double renal depth.
韩萍萍，李玲，刘杰，王猛，
金超岭，郑玉民. 肾脏深度对肾动态显像测定肾小球滤过率的影响[J]. 中国医疗设备, 2017, 32(6): 66-69.
HAN Ping-ping, LI Ling, LIU Jie,
WANG Meng, JIN Chao-ling,
ZHENG Yu-min. Effect of Kidney Depth in Glomerular Filtration Rate Measured by Kidney
Dynamic Imaging. China Medical Devices, 2017, 32(6): 66-69.
