Abstract：Objective To estimate the left atrial appendage flow velocity (LAA-FV) with clinical
parameters, which were noninvasively detected in patients with paroxysmal atrial fibrillation (AF) via
trans-thoracic echocardiography (TTE). Methods Trans-esophageal echocardiography (TEE) and TTE
examinations were simultaneously performed in 90 cases of patients with non-valvular paroxysmal AF
during the period of showing sinus rhythm, thereby to assess the obtained echocardiography and clinical
parameters. Results LAA-FV (61±23) cm/s was significantly correlated with the time interval between
the initiation of P-wave on electrocardiogram (ECG) and that of A-wave of transmitral flow on TTE (PATMF,
r=?0.33, P<0.001), left atrial diameter (LAD, r=?0.32, P<0.001), ventricular septal a’ velocity via
tissue Doppler imaging (TDI, r=0.36, P<0.001), E/e’ratio (r=?0.27, P<0.001), E velocity of transmitral
flow (r=?0.21, P=0.007), E/A ratio of transmitral flow (r=?0.17, P=0.04), CHA2DS2-VASc score
(r=?0.14, P=0.03) and plasma B-type natriuretic peptide (BNP) level (r=?0.33, P=0.003). Multivariate
analysis revealed that PA-TMF (standardized regression coefficient γ=?0.16, P=0.04), a’velocity
(γ=0.25, P=0.005) and LAD (γ=?0.21, P=0.02) were independent predictors of LAA-FV (multiple
correlation coefficient R=0.43; P<0.001). Conclusion Clinical parameters of atrial remodeling, such
as decreased a’velocity, increased LAD and PA-TMF under sinus rhythm, could be regarded as useful
predictors of left atrial blood stasis in patients with non-valvular paroxysmal AF.
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WANG Xiao-xiaa, LI Fang-yuanb,
LIU Hai-boa. Trans-Thoracic Echocardiographic Assessment of Left Atrial Blood Stasis
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