Abstract：Objective To explore the diagnostic value of time spatial labeling inversion pulse (Time-
SLIP) technology in the staging of chronic kidney disease (CKD). Methods 31 patients clinically
diagnosed with CKD (including 5 patients with stage 1 CKD, 6 patients with phase 2 CKD, 8 patients
with stage 3 CKD, 6 patients with stage 4 CKD and 6 patients with stage 5 CKD) as well as 13 healthy
volunteers (normal control group) were included. All subjects received conventional MRI and renal
artery examination with the coronal Time-SLIP technology. Two experienced radiologists assessed the
branches of renal artery MR angiography on 3D-MIP reconstructed images, and studied the correlation
with staging of CKD. Results Compared with CKD group and normal control group, there were no
statistically significant differences in the branches shows of renal arteries between stage 1 CKD and
normal control group (P>0.05),the differences were significant betuseen stage 2~5 CKD and noumal
control group. Compared with each CKD group, there were no statistically significant differences in the
branches shows of renal arteries between phase CKD1 and CKD2, there were statistically significant
differences between other groups (P<0.05). There was an obvious correlation between the branches
shows of renal arteries and the staging of CKD (P＜0.01). There was a significant negative correlation
with the branches shows of renal arteries and SCr (P＜0.01), and a significant positive correlation with
the GFR (P＜0.01). Conclusion Using time-SLIP technology for renal artery has certain value in the
staging of CKD. It can be used as a noninvasive clinical evaluation of renal function tests.
许晓岚，黄丙仓，张宏艳，
徐雁，陆炜平，弋春燕. 时间-空间标记反转脉冲技术在慢性肾
脏病分期中的初步研究[J]. 中国医疗设备, 2016, 31(3): 70-73.
XU Xiao-lan,
HUANG Bing-cang,
ZHANG Hong-yan, XU Yan,
LU Wei-ping, YI Chun-yan. A Preliminary Study of Time Spatial Labeling Inversion Pulse
Technology in the Staging of Chronic Kidney Disease. China Medical Devices, 2016, 31(3): 70-73.
