Clinical Simulation of Airway Obstruction Leading to Altered Respiratory Waveforms
XIONG Wei1a, MAO Bin1a, CHEN Hanjian1b, HUANG Yongquan2, WANG Binquan1a, SUN Jing1a,
ZHANG Qian1a, FENG Jingyi1a,3
a. Shaanxi Province Center for Regenerative Medicine and Surgery Engineering Research; b. National Local Joint Engineering
Research Center for Precision Surgery & Regenerative Medicine, The First Affiliated Hospital of Xi’an Jiaotong University,
Xi’an Shaanxi 710061, China
Abstract：Objective By carrying out clinical simulation on altered respiratory waveforms caused by airway obstruction, to establish
the relationship between airway obstruction and the degree of altered respiratory waveforms, and verify the feasibility of real-time
visual monitoring of airways. Methods A respiratory simulation platform with controllable airway obstruction was built to collect
the corresponding respiratory waveforms under different airway obstruction. Waveform features were extracted, the coefficient of
variation, correlation coefficient and rms error were calculated, and the fitting relationship curve between the airway obstruction and
the respiratory waveform features was established based on the least square method. Results The rising peak, ascending gradient and
falling peak of the flow rate waveform in pressure-controlled ventilation mode and volume-controlled ventilation mode were strongly
correlated with the airway obstruction, and the correlation could be described by quadrics. Conclusion The quantitative description
of the relationship between airway obstruction and respiratory waveform characteristics verifies the feasibility of real-time visual
monitoring of airways, and provides a new idea for artificial airway management.
熊伟1a，毛彬1a，陈寒鉴1b，黄永全2，王彬权1a，孙静1a，张倩1a，冯靖祎1a,3. 气道异物淤积导致呼吸波形改变的
临床模拟研究[J]. 中国医疗设备, 2024, 39(3): 1-6.
XIONG Wei1a, MAO Bin1a, CHEN Hanjian1b, HUANG Yongquan2, WANG Binquan1a, SUN Jing1a,
ZHANG Qian1a, FENG Jingyi1a,3. Clinical Simulation of Airway Obstruction Leading to Altered Respiratory Waveforms. China Medical Devices, 2024, 39(3): 1-6.
