CT Radiomics for the Preoperative Accuracy of Microvascular Invasion in Hepatocellular
Carcinoma: A Meta-Analysis
HAN Lei1, ZHANG Tong1, SONG Jiamin2, HOU Yu2, WU Chao2, LIU Xiaolin1,2
1. Baotou Clinical College, Inner Mongolia Medical University, Baotou Inner Mongolia 014040, China;
2. Department of Imaging, Baotou Central Hospital, Baotou Inner Mongolia 014040, China
Abstract：Objective To evaluate the accuracy of a model constructed based on CT radiomics in predicting microvascular invasion
(MVI) of hepatocellular carcinoma (HCC) by using a Meta-analysis. Methods Relevant clinical trial literatures were collected from
Web of Science, Embase, PubMed, Cochrane, CNKI, Wanfang and CBM databases, and screened and summarized for analysis.
Statistical software was used to assess the quality and bias risk of the included literature, and sensitivity and specificity, positive
likelihood ratio, negative likelihood ratio, diagnostic ODDS ratio and their respective 95%CI were combined. Summary receiver
operating characteristic curve were plotted to obtain the Cochran-Q index and area under curve (AUC). Sensitivity analysis was
used to detect potential sources of heterogeneity and assess the presence of publication bias through Deek’s test. Results A total of
11 literatures were included. The combined sensitivity, combined specificity, combined positive likelihood ratio, combined negative
likelihood ratio, combined diagnostic ODDS ratio and AUC were 0.84 (95%CI: 0.79-0.89), 0.82 (95%CI: 0.76-0.86), 4.67 (95%CI:
3.57-6.11), 0.19 (95%CI: 0.14-0.26), 24.53 (95%CI: 15.40-39.07) and 0.90 (0.87-0.92). Conclusion CT radiomics model has high
predictive efficacy for MVI of HCC, which can be used as one of the noninvasive preoperative evaluation methods, and has a good
clinical application prospect.
基金资助:内蒙古自治区重点研发和成果转化计划项
目（ 2 0 2 2 Y F S H 0 0 7 6 ） ； 包头市卫生健康科技计划项目
（ w s j k w k j 0 3 5 ） ； 包头医学院创新团队发展计划（ b y j j -
zxtd-003）
通讯作者:
刘晓林
E-mail: 40742287@qq.com
引用本文:
韩磊1，张同1，宋佳敏2，侯雨2，邬超2，刘晓林1,2. 基于CT影像组学预测肝细胞癌微血管侵犯准确性的Meta分析[J]. 中国医疗设备, 2023, 38(8): 67-73.
HAN Lei1, ZHANG Tong1, SONG Jiamin2, HOU Yu2, WU Chao2, LIU Xiaolin1,2. CT Radiomics for the Preoperative Accuracy of Microvascular Invasion in Hepatocellular
Carcinoma: A Meta-Analysis. China Medical Devices, 2023, 38(8): 67-73.
