Abstract:Objective To explore the application value of 256-slice spiral DVCT (Dynamic Volume Computerized Tomography) in diagnosis of MMD (Moyamoya Disease). Methods Altogether 23 cases of MMD patients (MMD Group) and 18 healthy volunteers (Control Group) were selected and scanned by 256-slice spiral DVCT. The arterial peak sequence was taken as the original image and then processed with adoption of multiple techniques including VR (Volume Rending) and MIP (Maximum Intensity Projection). With input of the original images into the perfusion analysis software, CBV (Cerebral Blood Volume), CBF (Cerebral Blood Flow), MTT (Mean Transit Time) and TTP (Time to Peak) values were acquired. And comparisons and statistical analysis were made between CT perfusion parameters of the distribution areas in ACA (Anterior Cerebral Arteries), MCA (Middle Cerebral Arteries) and PCA (Posterior Cerebral Arteries). Results In contrast with Control Group, patients in MMD Group showed longer TTP and MTT as well as larger CBV of the distribution areas in ACA and MCA with statistically significant differences (P<0.01); while, the CBF in ACA and MCA as well as the cerebral CT perfusion parameters in PCA between two groups had no statistical differences (P>0.05). Conclusion The 256-slice spiral DVCT revealed its advantages in successful display of the locations of vascular lesions, the degree of stenosis and changes of the abnormal sub-cranial vascular network, which provided significant guidance for diagnosis of MMD.
高青,崔慧,贾慧娟,史朴军,高伟. 256层螺旋CT动态容积扫描在烟雾病诊断中的应用价值[J]. 中国医疗设备, 2015, 30(7): 40-42.
GAO Qing, CUI Hui, JIA Hui-juan, SHI Pu-jun,GAO Wei. Application Value of 256-Slice Spiral Dynamic Volume CT in Diagnosis of Moyamoya Disease. China Medical Devices, 2015, 30(7): 40-42.