Abstract:Objective To explore the effectiveness of application of Young’s modulus value of shearing
wave elastography imaging technique in differential diagnosis of benign and malignant thyroid nodules.
Methods A total of 186 patients with thyroid nodules underwent real-time shear wave elasticity imaging.
Their ROC (Receiver Operating Characteristic) curves were drawn to acquire the optimal critical value of
benign and malignant thyroid nodules. Results There were 90 benign nodules and 129 malignant nodules
in the total 219 thyroid lesions. The mean, maximum and minimum Young’s modulus value of benign
nodules was (46.11±19.49), (69.13±32.26) and (13.12±7.29) kPa respectively, whereas the mean,
maximum and minimum Young’s modulus value of malignant ones was (81.22±21.99), (104.45±42.36)
and (24.76±10.91) kPa respectively, with statistically significant difference (P<0.01); The AUC (Area
under the Curve) of the ROC curve of maximum and the mean Young’s modulus value was respectively
0.783 and 0.893 (P<0.05). Taking 80.5 kPa as the threshold of maximum Young’s modulus value, the
sensitivity was 75.4% and specificity was 73.3%. Taking 63.5 kPa as the threshold of mean Young’s
modulus value, the sensitivity was 80.8% and specificity was 85.66%. Conclusion Young’s modulus
value of real-time shear wave elasticity imaging could directly and quantitatively reflect the hardness
of thyroid nodules, which provided an effective new method for the differential diagnosis of benign and
malignant thyroid nodules, and had broad clinical application prospect.
黄泽健,阚娜. 超声弹性成像技术诊断良恶性甲状腺结节效果的研究[J]. 中国医疗设备, 2016, 31(11): 50-52.
HUANG Ze-jian, KAN Na. Study on the Effectiveness of Application of Ultrasound Elastography
in Diagnosis of Benign and Malignant Thyroid Nodules. China Medical Devices, 2016, 31(11): 50-52.