Abstract：Objective To explore the clinical value of new dual-energy CT dual-source virtual scan in the diagnosis of solitary pulmonary nodule (SPN). Methods 49 patients with SPNs treated in our hospital from January 2013 to May 2014 were examined by CT conventional scan and dual-energy enhancement scan. Then the virtual scan images, iodine images and single energy images were obtained through softwares. The CT values, noises, signal to noise ratios, diameters of SPNs, calcification detection rates, enhancement values, CT values of iodine images, diagnostic accuracies, slopes of spectrum curves, ratios of iodine-based value and radiation doses were compared between real scan and virtual scan. Results There were no significant differences between the two scan methods on CT value, noise, signal to noise ratio and SPN diameter (P＞0.05). There were significant differences between the two scan methods on enhancement value and CT value (P＜0.05). The calcification detection rate of virtual scan was 93.02% according to real scan. The specificity of virtual scan in diagnosing SPNs was 92.86% while the sensitivity and accuracy of CT values of iodine images in diagnosing SPNs were 77.14% and 71.43%. The slops of spectrum curves of benign SPNs and malignant SPNs were (0.72±0.34) and (1.02±0.59). The iodine base value ratios of benign SPNs and malignant SPNs were (0.27±0.11) and (0.22±0.08). There were no differences between benign SPNs and malignant SPNs on the slop of spectrum curves and iodine base value ratio (P＞0.05). There were no significant differences between conventional scan and enhancement scan on radiation dose (P＞0.05). Conclusion The new dual-source and dual-energy CT virtual scan is important for the differential diagnosis of benign SPNs and malignant SPNs.
李海文，杨高忠. 新双源CT双能虚拟平扫技术在孤立性肺结节诊断中的应用价值[J]. 中国医疗设备, 2014, 29(9): 145-148.
LI Hai-wen, YANG Gao-zhong. Application Value of New Dual-Source and Dual-Energy CT Virtual Scan in the Diagnosis of Solitary Pulmonary Nodule. China Medical Devices, 2014, 29(9): 145-148.
Chen ZJ,Le HB,Zhang YK,et al.Microvessel density and expression of thrombospondin-1 in non-small cell lung cancer and their correlation with clinicopathological features[J].J Int Med Res,2009,37(2):551-556.
Sai M,Mori H,Kiyonaga M,et al.Peripancreatic lymphatic invasion by pancreatic carcinoma:evaluation with multi-detector row CT[J].Abdom Imaging,2010,35(2):154-162.
