Abstract:Objective To investigate the effects of the left and right hepatic duct, extrahepatic biliary duct and gallbladder high frequency ultrasound imaging in diagnosis of BA (Biliary Atresia) and IHS (Infantile Hepatitis Syndrome). Methods Through examinations of 58 obstructive jaundice infants by high frequency ultrasonography, prospective observations of the ultrasonograms obtained were made on the left and right hepatic duct, the upper extrahepatic biliary duct, the size, morphology and post-breastfeeding changes (until 2.5 h after breast-feeding or the contraction rate>50%) of gallbladder as well as triangular fibrotic mass and cyst echoes in hepatic hilum. The clinical diagnosis or operation results were taken as the reference so as to make comparisons with the examination results. Results There were 28 cases of BA and 30 IHS. Among 28 patients with BA, the gallbladder of 26 patients were revealed in 4 different conditions without display of the left and right hepatic duct and extrahepatic biliary duct; the crevice-like left and right hepatic duct and extrahepatic biliary duct were found in 2 cases with rough wall and low echo; there were 22 patients with triangular fibrotic masses in hepatic hilum and 4 (the average age<3 months) without triangular fibrotic masses; 7 patients were revealed with cyst echo in the hepatic hilum. As for 30 IHS patients, their left and right hepatic ducts and extrahepatic biliary duct were all well displayed: 3 patients were misdiagnosed as BA with the features of the crevice-like left and right hepatic ducts and extrahepatic biliary duct, rough wall and low echo; the gallbladder of 27 patients were revealed in 4 different conditions; cyst echo was found in the hepatic hilum in 3 patients. The differences between BA and IHS were of statistical significance (P=0.00) in visualization of the left and right hepatic ducts and the extrahepatic biliary duct. Statistically significant differences (P=0.01) existed between the unrevealed left & right hepatic duct, extrahepatic biliary duct and the triangular fibrotic mass found in the hepatic in the diagnosis of BA, among which there were statistically significant differences (P=0.01) in patients (age<3 months) and no statistical significance (P=1.00) in patients (age>3 months). Conclusion With clear display of the left & right hepatic ducts and the extrahepatic biliary duct, the high frequency ultrasound is effective in the early diagnosis of BA and IHS. It is recommended to observe the infants until 2.5 h after breast-feeding so as to obtain the gallbladder contraction rate.
贺晓,高剑波,滑少华,于瑞娜,张瑞芳. 高频超声探查胆管及胆囊在胆道闭锁和婴儿肝炎综合征鉴别诊断中的价值[J]. 中国医疗设备, 2013, 28(10): 153-155.
HE Xiao, GAO Jian-bo, HUA Shao-hua, YU Rui-na, ZHANG Rui-fang. Effects of Biliary Duct and Gallbladder High Frequency Ultrasound Imaging in Differential Diagnosis of BA and IHS. China Medical Devices, 2013, 28(10): 153-155.
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