Effectiveness of DW MRI in Differential Diagnosis of Uterine Endometrial Lesions
DENG Kai1, WANG Wen-wen2, ZHANG Cheng-qi1, WANG Guang-li1, LI Wei1, PANG Tao1, WANG Xin-yi1, SHI Hao1
1. Department of CT-MR, Qianfoshan Hospital Affiliated to Shandong University, Jinan Shandong 250014, China;2. Department of CT, Shandong Medical Imaging Research Institute, Jinan Shandong 250021, China
Abstract：Objective To evaluate the effectiveness of DW MRI (Diffusion-Weighted Magnetic Resonance Imaging) in differential diagnosis of uterine endometrial lesions through analysis of the ADC (Apparent Diffusion Coefficient) value. Methods Among 30 pathologically-confirmed uterine endometrial lesion patients undergoing conventional MRI and DWI (Diffusion Weighted Imaging), there were 18 cases of uterine endometrial carcinoma and 12 benign endometrial lesions. Based on the ADC values measured in all the lesions, comparisons were made respectively. Results The ADC value of uterine endometrial carcinoma was (0.88±0.11)×10-3mm2/s versus benign endometrial lesions’ (1.19±0.13)×10-3mm2/s with statistical difference (P＜0.01) between them. When 1.00×10-3mm2/s was taken as the threshold for differential diagnosis of benign (>1.00×10-3mm2/s) and malignant (<1.00×10-3mm2/s) uterine endometrial lesions, the sensitivity, specificity and accuracy of malignant uterine endometrial lesions were 88.9%, 100% and 93.3% respectively. Conclusion ADC measurement in DWI allowed for preliminary differentiate diagnosis of uterine endometrial lesions.
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DENG Kai, WANG Wen-wen, ZHANG Cheng-qi, WANG Guang-li, LI Wei, PANG Tao, WANG Xin-yi, SHI Hao. Effectiveness of DW MRI in Differential Diagnosis of Uterine Endometrial Lesions. China Medical Devices, 2014, 29(2): 161-163.
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