Abstract:Objective To evaluate the effect of a new low temperature plasma surgical system (NTS-100) on porcine skin incision
healing. Methods Skin samples were collected from both sides of the back and spine of 6 Bama miniature pigs, and the healing time
was 1 week, 2 weeks, 3 weeks, and 6 weeks respectively. The effects of scalpel, NTS-100, pulsed-electron avalanche knife (PEAK)
and high frequency electrosurgical scalpel on skin incision healing were compared. The evaluation indexes included blood loss, scar
width, degree of inflammatory cell infiltration and scar tensile strength. Results The hemostatic effect of NTS-100 was better than
that of scalpel (P<0.01). At each designated time point, scar width was less that of high frequency electrosurgical scalpel (P<0.05).
The infiltration of T lymphocytes and macrophages at 3 and 6 weeks of healing time was significantly less than that of high frequency
electrosurgical scalpel (P<0.01). The scar tensile strength at 3 weeks of healing time was higher than that of high frequency
electrosurgical scalpel (P<0.05). There was no statistically significant difference between new low temperature plasma surgical
system (NTS-100) and PEAK (P>0.05). Conclusion The new low temperature plasma surgical system (NTS-100) can reduce
postoperative scar formation, improve wound healing strength, and has reliable safety, which can meet the requirements of minimally
invasive surgery.
李捷,钟钰婷,赵进,管清钰,朱军永,王全胜,朱芸生,李席如. 新型低温等离子手术系统(NTS-100)对猪皮肤切割愈合的实验评价[J]. 中国医疗设备, 2021, 36(5): 51-56.
LI Jie, ZHONG Yuting, ZHAO Jin, GUAN Qingyu, ZHU Junyong, WANG Quansheng, ZHU Yunsheng, LI Xiru. Experimental Evaluation of a Novel Low Temperature Plasma Surgical
System (NTS-100) on Porcine Wound Healing. China Medical Devices, 2021, 36(5): 51-56.