1. Department of Radiotherapy, The Army Force Medical Center of PLA, Beijing 100142, China丨
2. Department of Radiotherapy, The General Hospital of PLA, Beijing 100853, China
Abstract：Objective To investigate the value of neutrophil to lymphocyte ratio (NLR) to evaluating the prognosis of patients with
stage III pancreatic cancer treated by radiotherapy. Methods A total of 41 patients with stage III pancreatic cancer were detected NLR
before radiotherapy. ROC curve was used to cut off the NLR with the highest sensitivity and specificity. The patients were divided
into high NLR group（NLR≥2.86）and low NLR group (NLR<2.86). The survival time was recorded and compared by Log-rank
method between two groups. Results The median survival time was 9 months in high NLR group and 21 months in low NLR group,
showing a significant difference by Log-rank method (P<0.05). There were no significant differences in the median survival time in
the age, gender, Karnofsky score, tumor location, carbohydrate antigen 19-9 level, surgical treatment before radiotherapy, regional
lymph node metastasis and synchronous chemotherapy (P>0.05). Conclusion NLR is closely related to the prognosis of pancreatic
cancer patients. High NLR is an indicator of poor prognosis for pancreatic cancer.
邸玉鹏1，孟玲玲2，任刚1，李宏奇1，常冬姝1，李平1，李晶1，康晓黎1，庞海峰1，王轩1，王颖杰1，夏廷毅1. 中性粒细胞/淋巴细胞比值对胰腺癌放疗预后的评估[J]. 中国医疗设备, 2021, 36(4): 149-152.
DI Yupeng1，MENG Lingling2，REN Gang1，LI Hongqi1，CHANG Dongshu1，LI Ping1，LI Jing1，KANG Xiaoli1，PANG Haifeng1，WANG Xuan1，WANG Yingjie1，XIA Tingyi1. Evaluation of Neutrophil to Lymphocyte Ratio for Prognosis of Pancreatic
Cancer After Radiotherapy. China Medical Devices, 2021, 36(4): 149-152.
