Effect of Pulsed and Continuous Dialysate Supply Patterns on Dialysis Adequacy
YIN Jia-ning1,2，LIU Zhi-cheng1
1.College of Biomedical Engineering, Capital Medical University, Beijing 100069, China; 2.Department of Blood Purification, Beijing Chao-yang Hospital, Capital Medical University, Beijing 100020, China
Abstract：Objective To observe the effect of pulsed and continuous dialysate supply patterns on dialysis adequacy of maintenance hemodialysis (MHD) patients. Methods 42 MHD patients were dialyzed through pulsed dialysate supply pattern (pulsed group) and continuous dialysate supply pattern (continuous group). Comparing the values of Kt/V and URR of patients in pulsed group with that of patients in continuous group, and analyzing the correlation between the ratios of blood flow and body weight and the values of Kt/V and URR based on the same flow velocity of dialysate. Results There was no significant difference between pulsed group and continuous group on the values of Kt/V and URR while the values of Kt/V and URR of the patients with high ratios of blood flow and body weight in pulsed group were significantly higher than that of patients with high ratios of blood flow and body weight in continuous group based on the same flow velocity of dialysate. Conclusion Pulse dialysate supply pattern which is beneficial to clear the hemodialysis solute is suitable for MHD patients with high ratios of blood flow and body weigh.
