Research Progress and Application of Noninvasive Vascular Endothelial
Function Detection Technology
LI Guixiang, HUANG Dequn, TANG Yuanliang, CHEN Jun, LIU Kai, YI Xiang，WU Xinshe
Guangdong Institute of Medical Instruments/National Engineering Research Center for Healthcare Devices, Medical Electrical
Devices and Polymer Materials Products Key Lab of Guangdong Province, Guangzhou Guangdong 510500, China
Abstract：Vascular endothelial function changes are closely related to cardiovascular disease, and endothelial structural
and functional damage is an important cause of atherosclerotic plaque formation and the earliest marker of vascular
disease. Noninvasive detection methods for evaluating endothelial function mainly include four methods including flow mediated
dilation (FMD), peripheral artery tonometry (PAT), optical plethysmography and noninvasive biochemical detection. Detection
of endothelial dysfunction could be achieved by using portable household or wearable endothelial function diagnostic equipment.
Timely intervention and treatment of vascular functional diseases could also prevent cardiovascular diseases. Moreover, periodic
tests of endothelial function were used to assess the effectiveness of a patient’s treatment plan, which could help clinicians and
cardiovascular patients better manage cardiovascular health. In this paper, the research progress and application of noninvasive
vascular endothelial function detection technology are analyzed to promote the development of noninvasive vascular endothelial
function detection technology and attract the national attention to vascular endothelial function detection.
李桂香，黄德群，唐元梁，陈军，刘凯，伊翔，吴新社. 无创血管内皮功能检测技术研究进展与应用[J]. 中国医疗设备, 2019, 34(12): 156-159.
LI Guixiang, HUANG Dequn, TANG Yuanliang, CHEN Jun, LIU Kai, YI Xiang，WU Xinshe. Research Progress and Application of Noninvasive Vascular Endothelial
Function Detection Technology. China Medical Devices, 2019, 34(12): 156-159.
