Multimodality Non-Invasive Imaging of Carotid Plaque Vulnerability: From Morphology
Character to Precision Diagnosis
HE Yu1a, JIN Ying2, LIU Jingxin1b, JIN Chunxiang1a
1. a. Department of Ultrasound; b. Department of Radiology, China-Japan Union Hospital of Jilin University, Changchun Jilin 130033, China;
2. Department of Breast Surgery, The First Hospital of Jilin University, Changchun Jilin 130021, China
Abstract：Characters of carotid plaque have been the focus of inspections in imaging modalities besides stenosis, which also
indicate the common phenotype of atherosclerosis. The term“vulnerable plaque”is used to refer to an atherosclerotic plaque
that is prone to rupture and the formation of thrombosis, which can lead to several cardiovascular and cerebrovascular events.
Features of vulnerable plaque include surface ulceration, intraplaque hemorrhage, a thin fibrous cap, a large lipid necrotic core,
calcification, inflammation and neovascularization. They interact with each other and plaque vulnerability depends on joints
effects. Although plaque information of morphology, metabolism and biology can be shown by imaging modalities, currently
there is no single imaging modality that can reliably identify the vulnerable plaque in relation to development of future stroke.
Therefore, multimodality imaging was an effect way to observe features of plaque from different angles, which contributes to
an integral, objective evaluation of plaque components and make a precision diagnosis of vulnerable plaque.
何雨1a，金颖2，刘景鑫1b，金春香1a. 多模态成像无创评价颈动脉斑块易损性：从形态显像到精准诊断[J]. 中国医疗设备, 2019, 34(7): 10-14.
HE Yu1a, JIN Ying2, LIU Jingxin1b, JIN Chunxiang1a. Multimodality Non-Invasive Imaging of Carotid Plaque Vulnerability: From Morphology
Character to Precision Diagnosis. China Medical Devices, 2019, 34(7): 10-14.
