Abstract：Objective To develop some methodological basics of selecting the volume of interest (VOI) for 18F-FET PET glioma
images. Methods First, a standard blank scan was performed using a 68Ge rod source, followed by a 15 min transmission scan of
the subject to obtain attenuation correction data. The 25 subjects with glioma were then injected 200 MBq of 18F-FET intravenous
after fasting. Each subject completed PET dynamic scans within 40 min after injection, which was divided into 16 time periods, each
lasting between 1 and 5 min. The resulting 16 frames of images data were reconstructed by filtered back-projection using a Shepp
filter and were corrected for scatter and attenuation. For further evaluation, data were transferred to a workstation. Motion of the
patient’s head were checked with a Matlab program and corrected with MPI-tool. Afterwards another image analysis software Pmod
was used to evaluate the dynamic data. At last the result time-activity curves were comparatively plotted, so that the data of patients
with different types could be analyzed. Results The head artifact image is not suitable for this method. Select the threshold of 50%
of the VOI can get the most accurate results. Conclusion The most accurate results can be obtained by contour contouring method
using 50% threshold VOI for 18F-FET brain gliomas.
胡彬1，胡海勇2. 基于体积感兴趣区的18F-FET PET脑胶质瘤分析方法研究[J]. 中国医疗设备, 2018, 33(6): 51-54.
HU Bin1, HU Haiyong2. Volume of Interest Based 18F-FET PET Image Analysis Method for Gliomas. China Medical Devices, 2018, 33(6): 51-54.
