Discussion on the Changes of Clinical Target Volume and Normal Tissue Volume for Patients with Prostate Cancer in the Whole Pelvic Irradiation
WANG Dan, SHA Xiang-yan, LIN Hai-lei
Department of Radiotherapy, Beijing Hospital, Beijing 100730, Chinalume of 5 patients were compared while the changing curves of rectum volumes were drawed within one week.
Abstract：Objective To investigate the changes of clinical target volume and normal tissue volume for patients with prostate cancer in the whole pelvic irradiation. Methods According to the CT images collected from the initial IMRT positioning and the secondary IMRT positioning after the whole pelvic irradiation (50 Gy) of 16 patients with prostate cancer treated from Jan 2011 to Dec 2013 in our hospital, clinical target volume (CTV), bladder volume and rectum volume as well as the external volume which was within the extended scope (the extended distance was 5 cm) of planning target volume (PTV) were delineated to evaluate the body weight changes of the patients. The changes of the above parameters were also compared with the statistical method. Then the changes of rectum volume of 5 patients were compared while the changing curves of rectum volumes were drawed within one week. Results There were significant differences between the initial IMRT positioning and the secondary IMRT positioning on the average CTV volume and the average rectum volume (P＜0.05) while there were no significant differences between the initial IMRT positioning and the secondary IMRT positioning on the average bladder volume and the average external volume (P＞0.05). However, the maximum bladder volume of one patient in the secondary IMRT positioning was 2.5 times than that in the initial IMRT positioning, which indicated that the individualized changes of bladder volume were significant. Conclusion Image guidance with reasonable frequency, the secondary IMRT positioning and plan modification should be used in the whole pelvic irradiation of patients with prostate cancer.
王丹，沙翔燕，林海磊. 前列腺癌患者全盆腔照射后靶区与正常组织体积变化探讨[J]. 中国医疗设备, 2014, 29(6): 118-120.
WANG Dan, SHA Xiang-yan, LIN Hai-lei. Discussion on the Changes of Clinical Target Volume and Normal Tissue Volume for Patients with Prostate Cancer in the Whole Pelvic Irradiation. China Medical Devices, 2014, 29(6): 118-120.
