Abstract：Objective To compare the dosimetric distribution of Intensity Modulated Radiotherapy
(IMRT) together with 3-Dimensional Conformal Radiation Therapy (3D-CRT) and simple IMRT for
breast cancer after radical surgery in order to provide the basis for breast cancer radio therapy. Methods
Altogether 20 breast cancer patients were collected. For each patient, the combination of IMRT and CRT
as well as simple IMRT were designed with the prescription dose of 50 Gy /25 times so as to compare
the dosimetric differences in Planning Target Volume (PTV) and Organs at Risk (OAR) of two plans.
Results The PTV V95% of two plans were similar [(99.18±0.32)% and (99.43±0.47)% respectively]
without statistically significant difference (P>0.05); V105% and V110% of IMRT together with 3D-CRT and
simple IMRT were similar without statistically significant difference (P>0.05). Conformity Index (CI)
and Homogeneity Index (HI) of combined plans were superior than those of simple IMRT, (P<0.05). In
contrast with simple IMRT, ipsilateral lung V30, V20, V5 of combined plans were reduced by 2.68%, 3.25%
and 27.38% respectively (P<0.05); cardiac V30, V40 and V50 were reduced by 3.18%, 2.27% and 1.52%
respectively (P<0.05).Conclusion Compared with simple IMRT, combination of IMRT and 3D-CRT
achieved better effects in dose distribution and CI and reduced the irradiation dose of lung, heart and
other vital organs, which showed better application effects.
阮长利，宋启斌，胡钦勇，
付敬国，张钧. 乳腺癌根治术后适形和调强混合放疗计划与单纯调强放疗计划的剂量学比较[J]. 中国医疗设备, 2016, 31(11): 116-118.
RUAN Chang-li, SONG Qi-bin,
HU Qin-yong, FU Jing-guo,
ZAHNG Jun. Dosimetry Comparison of IMRT with 3D-CRT and Simple IMRT for Breast
Cancer after Radical Surgery. China Medical Devices, 2016, 31(11): 116-118.
