Abstract：Objective To evaluate the significance of clinical application of diffusion weighted imaging (DWI) in the diagnosis of radiation-induced brain injury after radiotherapy for nasopharyngeal carcinoma. Methods 30 patients with nasopharyngeal carcinoma underwent MRI and DWI examination at different points: before the radiation therapy, 3 d after radiotherapy for the first time, immediately after the radiotherapy , and 3 months, 6 months, and 12 months after the radiotherapy. The ADC values in different periods were analyzed. Meanwhile, 30 healthy volunteers were also studied as the control group. Results The ADC values of bilateral temporal lobe in volunteers and nasopharyngeal carcinoma patients before radiotherapy had no statistical difference.The ADC value checked three days after radiotherapy for the first time and the ADC value checked at the end of the radiotherapy as well as the value checked three months after the radiotherapy were lower than the ADC values in pre-radiotherapy patients (P<0.05). The ADC values checked at 6 and 12 months after the radiotherapy showed no difference from the ADC value in pre-radiotherapy period. Conclusion DWI is an ideal mean to detect early radiation-induced brain injury．
梁杰，覃飞，陈伟华，黄柱飞. DWI技术在鼻咽癌早期放射性脑损伤中的应用价值[J]. 中国医疗设备, 2016, 31(1): 59-61.
LIANG Jie, QIN Fei, CHEN Wei-hua, HUANG Zhu-fei. Application Value of DWI in Early Radiation-induced Brain Injury after Radiotherapy for Nasopharyngeal Carcinoma. China Medical Devices, 2016, 31(1): 59-61.
