Effectiveness of Application of Non-Contrast 3.0T Three-dimension Time-of-Flight MR Angiography in Diagnosis of Vertebral Artery Ostium Stenosis
ZHAO Li-dong1, LIU Xiao-min2, GUO Qian1, BAI Min2
1. Department of Imaging, Liaocheng Brain Hospital, Liaocheng Shandong 252000, China; 2. Department of Radiology, Liaocheng People’s Hospital, Liaocheng Shandong 252000, China
Abstract：Objective To explore the feasibility and diagnostic accuracy of 3D time-of-flight MR angiography (3D TOF MRA) in the vertebral artery ostium stenosis at 3.0T MR. Methods The 3D TOF MRA and DSA (Digital Subtraction Angiography) images of 35 patients (70 vertebral arteries) who had been clinically diagnosed as suspected vertebral artery ostium stenosis in the hospital from September 2010 to December 2013 were retrospectively reviewed. Results Altogether 31 cases of vertebral artery ostium stenoses were confirmed by using DSA versus 37 cases as well as 11 false positives and 5 false negatives by using 3D TOF MRA. Taking DSA as the golden standard, the sensitivity, specificity, PPV and NPV of 3D TOF MRA in detection of the stenosis in the vertebral ostium were 83.9%, 68.6%, 70.3% and 82.8%, respectively. The Kappa value and Youden index of the 3D TOF MRA and DSA for the detection of vertebral ostial stenosis were 0.519 and 52.5% respectively with statistically significant differences (P＜0.001). Conclusion Non-contrast 3.0T 3D TOF MRA could be used for detection of the vertebral artery stenosis. Although it had relatively higher false-positive rate, it demonstrated higher sensitivity and could be taken as a feasible and noninvasive screening tool for the high risk population with related symptoms.
赵立冬，刘晓敏，郭茜，白敏. 非增强3.0T磁共振头颈部3D TOF MRA在椎动脉开口狭窄诊断中的应用价值[J]. 中国医疗设备, 2015, 30(11): 53-55.
ZHAO Li-dong, LIU Xiao-min, GUO Qian, BAI Min. Effectiveness of Application of Non-Contrast 3.0T Three-dimension Time-of-Flight MR Angiography in Diagnosis of Vertebral Artery Ostium Stenosis. China Medical Devices, 2015, 30(11): 53-55.
Gulli G,Khan S,Markus HS.Vertebrobasilar stenosis predicts high early recurrent stroke risk in posterior circulation stroke and TIA[J].Stroke,2009,40(8):2732-2737.
[1]
Gulli G,Khan S,Markus HS.Vertebrobasilar stenosis predicts high early recurrent stroke risk in posterior circulation stroke and TIA[J].Stroke,2009,40(8):2732-2737.
[2]
Maquardt L,Kuker W,Chandratheva,et al.Incidence and prognosis of ≥50% symptomatic vertebral or basilar artery stenosis:prospective population-based study[J].Brain,2009,132:982-988.
[3]
Marckmann P,Skov L,Rossen K,et al.Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging[J].J Am Soc Nephrol,2006,17(9):2339-2362.
[4]
Gaa J,Weidauer S,Requardt M,et al.Comparison of intracranial 3D-ToF-MRA with and without parallel acquisition techniques at 1.5T and 3.0T:preliminary results[J].Acta Radiol,2004,45(3):327-32.
[1]
Gulli G,Khan S,Markus HS.Vertebrobasilar stenosis predicts high early recurrent stroke risk in posterior circulation stroke and TIA[J].Stroke,2009,40(8):2732-2737.
[2]
Maquardt L,Kuker W,Chandratheva,et al.Incidence and prognosis of ≥50% symptomatic vertebral or basilar artery stenosis:prospective population-based study[J].Brain,2009,132:982-988.
[4]
Gaa J,Weidauer S,Requardt M,et al.Comparison of intracranial 3D-ToF-MRA with and without parallel acquisition techniques at 1.5T and 3.0T:preliminary results[J].Acta Radiol,2004,45(3):327-32.
[2]
Maquardt L,Kuker W,Chandratheva,et al.Incidence and prognosis of ≥50% symptomatic vertebral or basilar artery stenosis:prospective population-based study[J].Brain,2009,132:982-988.
[3]
Marckmann P,Skov L,Rossen K,et al.Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging[J].J Am Soc Nephrol,2006,17(9):2339-2362.
[3]
Marckmann P,Skov L,Rossen K,et al.Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging[J].J Am Soc Nephrol,2006,17(9):2339-2362.
[4]
Gaa J,Weidauer S,Requardt M,et al.Comparison of intracranial 3D-ToF-MRA with and without parallel acquisition techniques at 1.5T and 3.0T:preliminary results[J].Acta Radiol,2004,45(3):327-32.
