Application Value of Transcranial Doppler Ultrasound and Ultrasonic Measurement of ONSD
in Increased Intracranial Hypertension in Patients with Craniocerebral Injury
LI Qi, REN Yongfeng, WANG Zhou, LI Jian, YIN Yanhua, TANG Kun
Department of Ultrasound, The People’s Hospital of Bozhou, Bozhou Anhui 236800, China
Abstract：Objective To explore the application value of transcranial Doppler ultrasound (TCD) and ultrasonic measurement of optic
nerve sheath diameter (ONSD) in increased intracranial hypertension in patients with craniocerebral injury. Methods Clinical data
of 160 patients with craniocerebral injury from January 2021 to December 2022 were retrospectively analyzed. The patients were
divided into observation group (n=80) and control group (n=80) based on the presence of increased intracranial hypertension. They
were measured by TCD and ONSD. The ONSD and TCD parameters of the two groups were compared. The relationship between
increased intracranial hypertension with ONSD and TCD parameters was analyzed. The diagnostic efficacy of ONSD value, mean
velocity (Vm), systolic peak flow velocity (Vs), resistance index (RI) and pulse index (PI) was analyzed by establishing a receiver
operating characteristic (ROC) curve model. Results The ONSD values (5.44±1.16) mm, RI (0.77±0.21), and PI (2.32±1.18)
were higher in the observation group than those in the control group, Vs (112.58±26.63) cm/s and Vm (48.83±18.96) cm/s were
lower than those of the control group (P<0.05). In the severe group, the ONSD values (6.16±1.13) mm, RI (0.90±0.21), PI
(3.63±1.25) were higher than those in the moderate and mild groups. The Vs (100.83±30.80) cm/s and Vm (30.71±13.36) cm/s
were lower than those in the moderate and mild groups (P<0.05). The increased intracranial hypertension was positively correlated
with ONSD values, RI and PI (r=0.517, 0.569 and 0.652; P<0.001) and was negatively correlated with Vs and Vm (r=-0.340, -0.703;
P<0.001). Through ROC curve analysis, the area under curve of ONSD value, Vs, Vm, RI, PI and combined diagnosis of severe
increased intracranial hypertension were 0.806, 0.670, 0.921, 0.809, 0.960 and 0.996, respectively. Conclusion The TCD and ONSD
have positive significance in evaluating the changes of intracranial hypertension in patients with craniocerebral injury. Ultrasonic
spectrum images can directly reflect the changes of intracranial hypertension, and ONSD values can be changed due to the increase
of intracranial hypertension.
李琦，任永凤，王洲，李健，殷延华，唐坤. 经颅多普勒超声及超声测量视神经鞘直径
在颅脑损伤患者颅内压增高中的应用价值[J]. 中国医疗设备, 2024, 39(2): 148-153.
LI Qi, REN Yongfeng, WANG Zhou, LI Jian, YIN Yanhua, TANG Kun. Application Value of Transcranial Doppler Ultrasound and Ultrasonic Measurement of ONSD
in Increased Intracranial Hypertension in Patients with Craniocerebral Injury. China Medical Devices, 2024, 39(2): 148-153.
