Abstract:Objective To study the correlation between dual-phase multi-slice CT (MSCT) parameters and pulmonary function in
patients with chronic obstructive pulmonary disease (COPD). Methods A total of 160 COPD patients examined in the imaging center
of the Kashgar First People’s Hospital from May 2020 to October 2021 were retrospectively selected as the COPD group, including
75 cases of pulmonary function classification grade 1, 54 cases of grade 2, 20 cases of grade 3 and 11 cases of grade 4, and another
40 healthy people were selected as the control group during the same period. Pulmonary function was examined by Glatt Spirostik
spirometer and dual-phase MSCT with a Siemens Somatom Definition Flash 64-slice spiral CT was performed. Pulmonary function
indicators and dual-phase MSCT parameters between the two groups were compared, and the correlation between pulmonary
function indicators and dual-phase MSCT parameters was analyzed by Pearson/Spearman correlation analysis in COPD patients.
Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of dual-phase CT scan parameters for the
classification of pulmonary function in COPD patients. Results Compared with the control group, the COPD group’s vital capacity
(VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, volume difference all significantly
decreased, while residual volume (RV), total lung capacity (TLC), RV/TLC, deep end-inspiratory volume, deep end-expiratory
volume, and volume ratio all significantly increased (P<0.05). In COPD patients with pulmonary function grades 1, 2, 3, and 4,
the deep end-inspiratory volume, deep end-expiratory volume, and volume ratio increased sequentially, and the volume difference
decreased sequentially (P<0.05). Pearson/Spearman correlation analysis showed that deep end-inspiratory volume, deep endexpiratory
volume and volume ratio were negatively correlated with VC, FVC, FEV1, FEV1/FVC and positively correlated with RV,
TLC, RV/TLC in COPD patients (P<0.05). The volume difference was positively correlated with VC, FVC, FEV1, FEV1/FVC and
negatively correlated with RV, TLC, and RV/TLC (P<0.05). The ROC curve showed that the dual-phase MSCT parameters deep endinspiratory
volume, deep end-expiratory volume, volume difference and volume ratio had certain diagnostic value for pulmonary function grading in COPD patients. Conclusion In COPD patients, the dual-phase MSCT parameters of deep inspiratory volume,
deep end-expiratory volume, and volume ratio were significantly increased, and the volume difference was significantly decreased.
These parameters are closely related to pulmonary function, which can provide referring information for the evaluation of pulmonary
function in COPD patients.
邱娅a,戴国朝a,周仁冰a,吴仕吉b,郝月a,苏文静a,董家科a,邹科a. COPD患者CT双期扫描参数与肺功能的相关性研究[J]. 中国医疗设备, 2022, 37(6): 76-80.
QIU Yaa, DAI Guochaoa, ZHOU Renbinga, WU Shijib, HAO Yuea, SU Wenjinga, DONG Jiakea, ZOU Kea. Study on the Correlation Between Dual-Phase MSCT Parameters and
Pulmonary Function in COPD Patients. China Medical Devices, 2022, 37(6): 76-80.