Abstract:Objective To investigate the 18F-FDG PET/CT features and diagnostic value of spinal tuberculosis in middle-aged and
elderly patients. Methods A retrospective analysis was conducted in 27 cases of pathologically confirmed or follow-up clinically
after treatment confirmed spinal tuberculosis from May 2010 to February 2019. CT and PET images were collected, and the PET/CT images
were analyzed using semi-quantitative standardized uptake values. Results Clinical symptoms of spinal tuberculosis in middle-aged
and elderly patients were not typical, and 18F-FDG PET/CT could simultaneously detect bone lesions outside the spine and multiple
lesions throughout the body. Totally 67 affected vertebrae were detected in 27 patients, which were divided into: fragmentary,
osteolytic, focal destruction sclerosing, subperiosteal and mixed type. The focal destruction sclerosing type and fragmentary type
were more common than the others. There was increased metabolism in the osteosclerosis area. Among them, 24 cases (88.9%)
showed significant increase in radioactivity uptake, which was circular uptake. Conclusion 18F-FDG PET/CT can not only provide
morphological features to detect other lesions in the whole body, but also provide metabolic features to evaluate lesion activity and
determine puncture site, which is of great significance for early diagnosis, treatment evaluation and management of patients with
spinal tuberculosis.
周晓红a,艾紫璇a,马兵a,刘晓飞a,王涛b. 18F-FDG PET/CT在中老年脊柱结核诊断中的应用价值[J]. 中国医疗设备, 2022, 37(5): 19-22.
ZHOU Xiaohonga, AI Zixuana, MA Binga, LIU Xiaofeia, WANG Taob. Value of 18F-FDG PET/CT in Diagnosis of Spinal Tuberculosis for Middle-Aged and Elderly Patients. China Medical Devices, 2022, 37(5): 19-22.