Abstract：Objectives To investigate the clinical feasibility and repeatability of a MLLSR [Modified Look-Locker FIESTA (Fast Imaging Employing Steady State Acquisition) Imaging with Saturation Recovery]-based quantitative T1 mapping technique in 3.0T CMR (Cardiac Magnetic Resonance) to evaluate the left ventricular myocardial T1native values in different segments. Methods Altogether 30 healthy volunteers were selected and scanned by CMR on the sequence of Cine imaging, T2WI and T1 mapping so as to perform quantitative measurement of ROI (Region of Interest) T1native values. Then, the independent-samples T test and ANOVA (Analysis of Variance) were deployed to analyze the difference of the T1native values in 17 segments of myocardium, different coronary arterial blood supply areas, age and gender. Results There were differences of the T1native values between some segmental myocardia(P<0.01). The mean myocardial T1native and T1native of blood pool were: (717.6±100.6) ms and (1208.9±224.2) ms at the base; (773.9±101.2) ms and (1281.2±251.7) ms in the middle; (955.4±191.1) ms and (1829.6±584.8) ms at the apex, respectively. Apical T1native values of myocardium and blood pool were higher than the basal and the middle (P<0.01). Also, statistically significant differences (F＝47.862, P<0.01) existed in T1native values of different coronary arterial blood supply areas. Conclusion The CMR MLLSR T1 mapping technique had demonstrated its excellent feasibility and repeatability, which revealed segmented variations in evaluation of left ventricular myocardial T1native values.
刘明熙，张挽时，张子衡，周振宇，解立志，孟利民，徐先荣，田建伟，龚万沣，祝红线，刘洁. T1 mapping定量技术评价左室不同区域心肌初始T1值的初步研究[J]. 中国医疗设备, 2015, 30(6): 33-38.
LIU Ming-xi, ZHANG Wan-shi, ZHANG ZI-heng, ZHOU Zhen-yu, XIE Li-zhi, MENG Li-min, XU Xian-rong, TIAN Jian-wei, GONG Wan-feng,ZHU Hong-xian, LIU Jie. A Preliminary Study of the Quantitative T1 Mapping Technique in Evaluation of the Native Left Ventricular Myocardial T1 Value in Different Segments. China Medical Devices, 2015, 30(6): 33-38.
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