Abstract:Objective To evaluate the potential of acquiring the diagnostic images of coronary CT angiography with prospective ECG-triggered high pitch flash spiral acquisition in low tube voltage combined with iterative reconstruction. Methods There were fifty patients whose BMI(body mass index ) <30 kg/m2 and heart rate ≤60/min, and their coronary CT angiography images were collected with prospective ECG-triggered high pitch flash spiral mode. The images reconstruction adopted the raw data-based filtered back projection (FBP) and iterative reconstruction (IR). Image quality was assessed with a 4-point scale standard. Results The average effective dose was 0.85±0.37 mSv. The noise of iterative reconstruction was significantly reduced, which is statistically different from the FBP. The data were (26.4±5.2)HU and (20.6±4.1) HU. The image quality score was lower for IR (1.9±1.1), which is statistically different from that of FBP(2.2±1.0)( P<0.0001). Among 728 coronary segments, there were 61 coronary segments of FBP and 38 segments of IR were scored 4 (P=0.07). For patients whose BMI = 24 kg/m2, the noise of evaluable image of IR was low. The SNR and CNR of coronary segments of IR were higher than those of FBP, which was statically important. Conclusion Prospective ECG-triggered high pitch flash spiral acquisition in low tube voltage combined with iterative reconstruction can provide sufficient image quality for selected patients.