Abstract:Objective The purpose of this study is to discuss the diagnostic value of different ADC values on ductal carcinoma in
situ (DCIS) so as to evaluate the preoperative prediction invasive component. Methods A total of 69 DCIS female patients with 70
lesions confirmed by pathology during June 2014 and October 2016 were included in this study; all of them underwent preoperative
MRI. We selected the highest and lowest ADC value from the region of interest, and calculated the difference value between them.
The differences between the DCIS and DCIS invasive component were compared. Results The minimum ADC value in DCIS
invasive component was much lower than that of DCIS (P=0.0037). The difference value between maximum ADC and minimum
ADC in DCIS invasive component was much higher than that of DCIS (P=0.0007). There was negative correlation between
minimum ADC value and difference value (r=0.65). ROC showed that the effective threshold-value of ADC maximum value less
than 1.1×10-3 mm2/s was contributed to identification of DCIS invasive component and DCIS, with sensibility and specificity of
72% and 77%. Similarly, the effective threshold-value of difference value of ADC higher than 0.23×10-3 mm2/s was also contributed
to identification of DCIS invasive component and DCIS, with sensibility and specificity of 68% and 76%. Conclusion Both the
minimum ADC value and the difference value between the minimum and maximum are helpful for identifying of DCIS invasive
component and DCIS, which can help to determine if the sentinel lymph node and axillary lymph node could be swept.
郭宏兵,刘菲,史新乐,赵一林,邹殿俊. ADC值对乳腺导管原位癌侵袭成分的研究价值[J]. 中国医疗设备, 2018, 33(5): 76-79.
GUO Hongbing, LIU Fei, SHI Xinle, ZHAO Yilin, ZOU Dianjun. Effect of ADC Values on Detection of Ductal Carcinoma in Situ. China Medical Devices, 2018, 33(5): 76-79.