Prior Image Constraint Reconstruction Method in 4D Micro-CT
SHEN Tao1, SUN Yi1,
WU Hua-zhen1, CHEN Gong2,
LUO Shou-hua1
1.School of Biological Sciences & Medical
Engineering, Southeast University, Nanjing
Jiangsu 210000, China; 2.Department of
Medical Engineering Section, Affiliated
Hospital of Nanjing University of TCM,
Nanjing Jiangsu 210029, China
Abstract:4D micro-CT imaging is a novelty and efficient method in disease surveillance and provides
a living dynamic imaging information. Traditional cardio-respiratory gating strategies and micro-
CT reconstruction methods have the disadvantages of long scanning time, high radiation dose, and
motion artifact in reconstruction image. In order to solve those problems of traditional methods, this
paper proposes a new 4D CT scanning and reconstruction method based on the gating technique
and the prior image constraint compressed sensing (PICCS) reconstruction algorithm. This method
utilizes the retrospective gating technique which demands continuous scanning of multiple rotations,
the reconstruction result of respiratory phase sorted projections is set as the prior image in the PICCS
reconstruction. The experimental results demonstrate that the proposed method can effectively obtain 4D
reconstruction images with no streaking artifacts. 4D micro-CT imaging using PICCS provides image
quality superior to FDK and OSART algorithms in both MSE and Peak Signal to noise ratio (PSNR)
calculations. This method can provide fast acquisition and better images over existing methods.