Research Progress on the Effect of Vagus Nerve Stimulation on Electroencephalogram of
Drug-Resistant Epilepsy
QU Zhichuang1,2, ZHANG Yuanyuan1,3, LUO Juan1,2, CHEN Xin1, SHU Haifeng1,2,3
1. Department of Neurosurgery, General Hospital of the Western Theater Command of the PLA, Chengdu Sichuan 610083, China;
2. Department of Neurosurgery, Affiliated Hospital of Southwest Medical University, Luzhou Sichuan 646000, China;
3. School of Medical, Southwest Jiaotong University, Chengdu Sichuan 610031, China
Abstract：Vagus nerve stimulation (VNS ) is an invasive technique of implanting electrodes into the cervical vagus nerve. As a
pharmacological adjuvant therapy, VNS has shown a good antiepileptic effect in clinical studies for the treatment of drug-resistant
epilepsy. However, the antiepileptic mechanism of vagal nerve stimulation is still unclear. In recent years, studies have studied
the changes of electroencephalogram in patients with refractory epilepsy after VNS, which might help to explain the antiepileptic
mechanism of vagal nerve stimulation. This article reviewed the mechanism of vagal nerve stimulation in the treatment of drugresistant
epilepsy and the clinical research progress of the electroencephalogram changes after VNS.
屈直闯1,2，张元元1,3，罗娟1,2，陈欣1，树海峰1,2,3. 迷走神经刺激术对药物难治性癫痫术后脑电影响的研究进展[J]. 中国医疗设备, 2022, 37(9): 155-158.
QU Zhichuang1,2, ZHANG Yuanyuan1,3, LUO Juan1,2, CHEN Xin1, SHU Haifeng1,2,3. Research Progress on the Effect of Vagus Nerve Stimulation on Electroencephalogram of
Drug-Resistant Epilepsy. China Medical Devices, 2022, 37(9): 155-158.
