Clinical Application of the Third Generation Dual Source CCTA Scan for
Size-Specific Dose Estimation
NIE Zhuang1,2，LEI Ziqiao1,2，FAN Wenliang1,2，YANG Ming1,2，YU Jianming1,2
1. Department of Radiology, Union Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology,
Wuhan Hubei 430022, China丨 2. Key Laboratory of Medical Molecular Imaging of Hubei Province, Wuhan Hubei 430022, China
Abstract：Objective To explore the feasibility of using size-specific dose estimation (SSDE) in the clinical application of
Coronary CT Angiography (CCTA) radiation dose assessment. Methods Retrospectively analyzed 453 cases of CCTA. All cases
were performed on the third generation dual-source Force CT with prospective ECG-gated triggered axial scan protocol. Volume
CT dose index (CTDIvol) and DLP were recorded on the device for each patient. The image data were transferred to Radimetrics
Workstation (Bayer) for radiation dose parameters computing, include organ dose doses (skin, lungs, heart), effective dose, patient
water equivalent diameter (WED) and SSDE. SSDE was calculated using a patient-specific parameter, WED, as reported by AIST
Working Group 220. Correlation between SSDE and organ dose were calculated respectively, and linear correlation analysis of
SSDE, CTDIvol and organ dose was performed. Results CTDIvol was about 22.4% lower than SSDE (19%-24.8%), and the difference
was statistically significant (P<0.05). There was significant positive correlation between SSDE and organ dose. Linear regression
analysis of the correlation between SSDE and organ dose: skin: P<0.001, r2=0.96, slope=0.13丨 lungs: P<0.001, r2=0.93, slope=0.70丨
heart: P<0.001, r2=0.95, slope=0.94. Linear regression analysis of the correlation between CTDIvol and organ dose: skin: P<0.00.1,
r2=0.94, slope=0.16丨 lungs: P<0.001, r2=0.89, slope=0.94丨 heart: P<0.001, r2=0.94, slope=1.25. The linear correlation between SSDE
calibrated by water equivalent diameter and organ dose was higher than that of CTDIvol. Conclusion SSDE can be used to evaluate
the dose level of the third-generation dual source CCTA.
聂壮1,2，雷子乔1,2，范文亮1,2，杨明1,2，余建明1,2. 第三代双源CCTA扫描体型特异性剂量估计的临床应用研究[J]. 中国医疗设备, 2021, 36(10): 149-152.
NIE Zhuang1,2，LEI Ziqiao1,2，FAN Wenliang1,2，YANG Ming1,2，YU Jianming1,2. Clinical Application of the Third Generation Dual Source CCTA Scan for
Size-Specific Dose Estimation. China Medical Devices, 2021, 36(10): 149-152.
