Clinical Value of 3.0 T MR Diffusion-Weighted Imaging and Apparent Diffusion Coefficient
in the Diagnosis of Gastric Cancer with Different Degrees of Differentiation
QI Xingliang
Department of Radiology, Beijing Pinggu Hospital, Beijing 101200, China
Abstract:To analyze the clinical value of 3.0 T MR diffusion-weighted imaging (DWI) and apparent diffusion coefficient
(ADC) in the diagnosis of different degrees of differentiation of gastric cancer. Methods Fifty-four patients with gastric cancer who
were diagnosed and treated in our hospital from October 2015 to March 2017 were selected in this study. According to the degree of
differentiation of gastric cancer, the patients were divided into three groups: low, medium and high differentiation. Then DWI and
ADC parameters of three groups of gastric cancer patients were obtained by using 3.0 T MR. The ADC values of three groups of
gastric cancer patients were evaluated by one-way anova with t test, and the LAVA reinforcement characteristics of three groups of
gastric cancer patients were evaluated by n (%) and χ2 test. The grade data of differentiation degree were compared between groups
and the clinical value was analyzed by rank sum test. Results All the 54 patients with gastric cancer showed high signal shadow
on DWI, high or slightly high signal shadow on T2WI, low or equal signal on T1WI, and LAVA showed enhanced lesions. Among
them, there were statistically significant differences in the enhancement characteristics of high, moderate and poorly differentiated
adenocarcinomas (Z=-5.2800, P=0.000). The ADC value of normal gastric wall (3.034±0.211)×10-3 mm2/s was significantly higher
than that of gastric cancer patients (1.121±0.186)×10-3 mm2/s. The difference was statistically significant (t=49.978, P=0.000). Both
DWI and LAVA+DWI images showed that the ADC value of poorly differentiated adenocarcinoma was significantly lower than that
of moderately and well differentiated adenocarcinoma, and the difference was statistically significant (P<0.05). Conclusion DWI
and ADC can effectively identify and diagnose different degree of differentiation of gastric cancer, while auxiliary LAVA can further
obtain more comprehensive parameter information, evaluate its biological behavior, which has high clinical diagnostic value.
齐星亮. 3.0 T MR扩散加权成像及表观扩散系数诊断胃癌不同分化程度的临床价值[J]. 中国医疗设备, 2019, 34(2): 80-84.
QI Xingliang. Clinical Value of 3.0 T MR Diffusion-Weighted Imaging and Apparent Diffusion Coefficient
in the Diagnosis of Gastric Cancer with Different Degrees of Differentiation. China Medical Devices, 2019, 34(2): 80-84.