Abstract：Objective The purpose of this article was to study the dosimetry difference between the
Auto-planning (AP) and conventional intensity-modulated radiotherapy (IMRT) in cervical cancer
patients. Methods Ten grade I～Ⅲ cervical cancer patients were selected to perform the analysis. AP
plan and IMRT plan were obtained by the Pinnacle3 V9.10 treatment planning system. The dose-volume
histogram, homogeneity index, conformity index, and the doses that received by the organs at risk (OARs)
were compared. Results Compared with the IMRT, the AP could generate treatment plan with lower
target region Dmax, and the statistical difference of AP was significant (P=0.001). But no statistical difference
was found in Dmin, Dmean, CI and HI of the target region. Superior results were found in bladder V50, rectum
V50, Dmean, caput femoris V30 and Dmean with statistical difference (P<0.05). The V30, V40, V45 in bladder, V40 in
rectum and caput femoris that texted by AP plan were lower than IMRT plan. Conclusions the AP plan could
achieve similar target dose distribution to IMRT plan. Meanwhile, the AP plan could lower the highest
dose in the target region. The hot spot and the illuminated of OARs were reduced at the same time.
王琳婧，王锐濠，雷怀宇，
李慧君，周露，张国前，张书旭. 基于Auto-Planning的宫颈癌调强放疗的剂量学研究[J]. 中国医疗设备, 2017, 32(6): 83-86.
WANG Lin-jing, WANG Rui-hao,
LEI Huai-yu, LI Hui-jun,
ZHOU Lu, ZHANG Guo-qian,
ZHANG Shu-xu. Dosimetric Study of Auto-Planning Based on Cervical Cancer Intensity-
Modulated Radiotherapy. China Medical Devices, 2017, 32(6): 83-86.
